Automatically summarizing patients’ main problems from daily progress notes using natural language processing methods helps to battle against information and cognitive overload in hospital settings and potentially assists providers with computerized diagnostic decision support. Problem list summarization requires a model to understand, abstract, and generate clinical documentation. In this work, we propose a new NLP task that aims to generate a list of problems in a patient’s daily care plan using input from the provider’s progress notes during hospitalization. We investigate the performance of T5 and BART, two state-of-the-art seq2seq transformer architectures, in solving this problem. We provide a corpus built on top of progress notes from publicly available electronic health record progress notes in the Medical Information Mart for Intensive Care (MIMIC)-III. T5 and BART are trained on general domain text, and we experiment with a data augmentation method and a domain adaptation pre-training method to increase exposure to medical vocabulary and knowledge. Evaluation methods include ROUGE, BERTScore, cosine similarity on sentence embedding, and F-score on medical concepts. Results show that T5 with domain adaptive pre-training achieves significant performance gains compared to a rule-based system and general domain pre-trained language models, indicating a promising direction for tackling the problem summarization task.

Concept normalization, the task of linking textual mentions of concepts to concepts in an ontology, is critical for mining and analyzing biomedical texts. We propose a vector-space model for concept normalization, where mentions and concepts are encoded via transformer networks that are trained via a triplet objective with online hard triplet mining. The transformer networks refine existing pre-trained models, and the online triplet mining makes training efficient even with hundreds of thousands of concepts by sampling training triples within each mini-batch. We introduce a variety of strategies for searching with the trained vector-space model, including approaches that incorporate domain-specific synonyms at search time with no model retraining. Across five datasets, our models that are trained only once on their corresponding ontologies are within 3 points of state-of-the-art models that are retrained for each new domain. Our models can also be trained for each domain, achieving new state-of-the-art on multiple datasets.

Concept normalization, the task of linking textual mentions of concepts to concepts in an ontology, is challenging because ontologies are large. In most cases, annotated datasets cover only a small sample of the concepts, yet concept normalizers are expected to predict all concepts in the ontology. In this paper, we propose an architecture consisting of a candidate generator and a list-wise ranker based on BERT. The ranker considers pairings of concept mentions and candidate concepts, allowing it to make predictions for any concept, not just those seen during training. We further enhance this list-wise approach with a semantic type regularizer that allows the model to incorporate semantic type information from the ontology during training. Our proposed concept normalization framework achieves state-of-the-art performance on multiple datasets.

Prior work has demonstrated that question classification (QC), recognizing the problem domain of a question, can help answer it more accurately. However, developing strong QC algorithms has been hindered by the limited size and complexity of annotated data available. To address this, we present the largest challenge dataset for QC, containing 7,787 science exam questions paired with detailed classification labels from a fine-grained hierarchical taxonomy of 406 problem domains. We then show that a BERT-based model trained on this dataset achieves a large (+0.12 MAP) gain compared with previous methods, while also achieving state-of-the-art performance on benchmark open-domain and biomedical QC datasets. Finally, we show that using this model’s predictions of question topic significantly improves the accuracy of a question answering system by +1.7% P@1, with substantial future gains possible as QC performance improves.

Recent studies have shown that pre-trained contextual word embeddings, which assign the same word different vectors in different contexts, improve performance in many tasks. But while contextual embeddings can also be trained at the character level, the effectiveness of such embeddings has not been studied. We derive character-level contextual embeddings from Flair (Akbik et al., 2018), and apply them to a time normalization task, yielding major performance improvements over the previous state-of-the-art: 51% error reduction in news and 33% in clinical notes. We analyze the sources of these improvements, and find that pre-trained contextual character embeddings are more robust to term variations, infrequent terms, and cross-domain changes. We also quantify the size of context that pre-trained contextual character embeddings take advantage of, and show that such embeddings capture features like part-of-speech and capitalization.

This paper presents the outcomes of the Parsing Time Normalization shared task held within SemEval-2018. The aim of the task is to parse time expressions into the compositional semantic graphs of the Semantically Compositional Annotation of Time Expressions (SCATE) schema, which allows the representation of a wider variety of time expressions than previous approaches. Two tracks were included, one to evaluate the parsing of individual components of the produced graphs, in a classic information extraction way, and another one to evaluate the quality of the time intervals resulting from the interpretation of those graphs. Though 40 participants registered for the task, only one team submitted output, achieving 0.55 F1 in Track 1 (parsing) and 0.70 F1 in Track 2 (intervals).

This paper presents the first model for time normalization trained on the SCATE corpus. In the SCATE schema, time expressions are annotated as a semantic composition of time entities. This novel schema favors machine learning approaches, as it can be viewed as a semantic parsing task. In this work, we propose a character level multi-output neural network that outperforms previous state-of-the-art built on the TimeML schema. To compare predictions of systems that follow both SCATE and TimeML, we present a new scoring metric for time intervals. We also apply this new metric to carry out a comparative analysis of the annotations of both schemes in the same corpus.